BDBM50248494 CHEMBL490968::N-(Pyridin-4-ylmethyl)-2-(1-(3-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-4-yl)benzenamine

SMILES FC(F)(F)c1cccc(c1)-n1cc(nn1)-c1ccccc1NCc1ccncc1

InChI Key InChIKey=PBSCJZOXINETHX-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50248494   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50248494(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Affinity DataKi:  80nMAssay Description:Binding affinity to VEGFR2 (unknown origin) at IC90 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50248494(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Affinity DataKi:  90nMAssay Description:Binding affinity to VEGFR2 (unknown origin) at IC50 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50248494(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Affinity DataIC50:  66nMAssay Description:Inhibition of VEGFR1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50248494(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Affinity DataIC50:  96nMAssay Description:Inhibition of VEGF-induced phosphorylation of VEGFR2 (unknown origin) by cell-based ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50248494(CHEMBL490968 | N-(Pyridin-4-ylmethyl)-2-(1-(3-(tri...)
Affinity DataIC50:  51nMAssay Description:Inhibition of VEGFR2 (unknown origin) by HTRF assay in presence of 2 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed