BDBM50248525 3-(1-(3-(dimethylamino)propyl)-2-phenethyl-1H-benzo[d]imidazol-5-yl)-N-hydroxyacrylamide::CHEMBL489331::US10201527, Compound 63::US10736881, Compound 63::US8551988, 63

SMILES CN(C)CCCn1c(CCc2ccccc2)nc2cc(\C=C\C(=O)NO)ccc12

InChI Key InChIKey=RSGFYZCTBZEMGX-SDNWHVSQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248525   

TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248525(3-(1-(3-(dimethylamino)propyl)-2-phenethyl-1H-benz...)
Affinity DataIC50:  162nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248525(3-(1-(3-(dimethylamino)propyl)-2-phenethyl-1H-benz...)
Affinity DataIC50:  162nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248525(3-(1-(3-(dimethylamino)propyl)-2-phenethyl-1H-benz...)
Affinity DataIC50:  162nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248525(3-(1-(3-(dimethylamino)propyl)-2-phenethyl-1H-benz...)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed