BDBM50249016 CHEMBL471543::N-Cyclopropylmethyl-14beta-4'-methylcinnamoyloxy-7,8-dihydrocodeinone

SMILES COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35OC(=O)\C=C\c1ccc(C)cc1

InChI Key InChIKey=TUZQURVIVXHNQP-WDGPPKDVSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50249016   

TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50249016(CHEMBL471543 | N-Cyclopropylmethyl-14beta-4'-methy...)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50249016(CHEMBL471543 | N-Cyclopropylmethyl-14beta-4'-methy...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50249016(CHEMBL471543 | N-Cyclopropylmethyl-14beta-4'-methy...)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50249016(CHEMBL471543 | N-Cyclopropylmethyl-14beta-4'-methy...)
Affinity DataEC50:  157nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed