BDBM50249030 CHEMBL3770346

SMILES COc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl

InChI Key InChIKey=CTEGQKDJTBWFHW-UHFFFAOYSA-N

Data  2 KI  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249030   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Intellisyn Pharma

Curated by ChEMBL
LigandPNGBDBM50249030(CHEMBL3770346)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]NMS from wild-type human mAChR2 expressed in Flp-in-CHO cell membranes in presence of mAChR2 agonist xanomeline after 90 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Intellisyn Pharma

Curated by ChEMBL
LigandPNGBDBM50249030(CHEMBL3770346)
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]NMS from wild-type human mAChR2 expressed in Flp-In-CHO cell membranes in presence of mAChR2 agonist acetylcholine after 90 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50249030(CHEMBL3770346)
Affinity DataEC50:  225nMAssay Description:Positive allosteric modulation of rat M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mob...More data for this Ligand-Target Pair