BDBM50249181 CHEMBL473392::N-(4-chlorobenzyl)-2-((2R,6S,E)-5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl)acetamide::N-(4-chlorobenzyl)-2-((2R,6S,E)-5,12-dioxo-2-phenyl-1-oxo-4-azacyclododec-8-en-6-yl)acetamide::Robotnikinin
SMILES Clc1ccc(CNC(=O)C[C@@H]2C\C=C\CCC(=O)O[C@@H](CNC2=O)c2ccccc2)cc1
InChI Key InChIKey=DRDSZZCLAHXSAE-BQIDRLATSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50249181
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+3nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to N-terminal Shh by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to N-terminal sonic hedgehog (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+3nMAssay Description:Inhibition of sonic hedgehog pathway in mouse NIH-3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human Shh-induced mouse C3H10T1/2 cell differentiation after 48 hrs by alkaline phosphatase reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of sonic hedgehog signaling in mouse Shh Light2 cells after 30 mins by Bright-Glo luciferase assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.10E+3nMAssay Description:Binding affinity to SHHMore data for this Ligand-Target Pair