BDBM50249263 (S)-2-amino-3-(4-(3-(biphenyl-4-yl)propoxy)phenylamino)-2-methyl-3-oxopropyl dihydrogen phosphate::CHEMBL473238
SMILES C[C@](N)(COP(O)(O)=O)C(=O)Nc1ccc(OCCCc2ccc(cc2)-c2ccccc2)cc1
InChI Key InChIKey=TXFZSDIRXYGOOU-VWLOTQADSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50249263
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 27.1nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 70.4nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.38nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.24nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human S1P1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair