BDBM50249514 CHEMBL474409::cis-(3,3-difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(pyrazin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone

SMILES FC1(F)CCN(C1)C(=O)[C@@H]1C[C@@H](CN1)N1CCN(CC1)c1cnccn1

InChI Key InChIKey=XFZMONZBKARRRP-KBPBESRZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249514   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50249514(CHEMBL474409 | cis-(3,3-difluoropyrrolidin-1-yl)((...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human plasma DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50249514(CHEMBL474409 | cis-(3,3-difluoropyrrolidin-1-yl)((...)
Affinity DataIC50:  540nMAssay Description:Inhibition of human recombinant DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50249514(CHEMBL474409 | cis-(3,3-difluoropyrrolidin-1-yl)((...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed