BDBM50249737 2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)isonicotinonitrile::CHEMBL522456

SMILES Fc1ccc(cc1)C1(CNC(=N1)c1cc(ccn1)C#N)c1ccc(F)cc1

InChI Key InChIKey=KEJJLAINBBOGHE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249737   

TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249737(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249737(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)
Affinity DataIC50:  101nMAssay Description:Displacement of [35S]N-[(4R)-1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]6-yl]methanesu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249737(2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed