BDBM5025 Oseltamivir::US10919856, POSITIVE CONTROL::ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate

SMILES [H][C@@]1(OC(CC)CC)C=C(C[C@H](N)[C@H]1NC(C)=O)C(=O)OCC

InChI Key InChIKey=VSZGPKBBMSAYNT-RRFJBIMHSA-N

Data  2 KI  125 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 5025   

TargetNeuraminidase(Influenza A virus (A/turkey/Italy/4426/2000(H7N1)))
Chulalongkorn University

LigandPNGBDBM5025(Oseltamivir | US10919856, POSITIVE CONTROL | ethyl...)
Affinity DataIC50:  25nMpH: 6.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) determination was carried out by using a 96-well microtitre plate as an array of reaction vessels. In the fir...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-structural protein 1(Influenza A virus (A/turkey/Italy/8000/2002(H7N3)))
Chulalongkorn University

LigandPNGBDBM5025(Oseltamivir | US10919856, POSITIVE CONTROL | ethyl...)
Affinity DataIC50:  0.200nMpH: 6.5 T: 2°CAssay Description:The 50% inhibitory concentration (IC50) determination was carried out by using a 96-well microtitre plate as an array of reaction vessels. In the fir...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus (A/turkey/Italy/4426/2000(H7N1)))
Chulalongkorn University

LigandPNGBDBM5025(Oseltamivir | US10919856, POSITIVE CONTROL | ethyl...)
Affinity DataIC50:  23.7nMpH: 6.5Assay Description:Practically in a microtitre plate, 90 μl of 33 mM MES pH 6.5 containing 4 mM CaCl2 were dispensed in each well, except for the first well of eac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-structural protein 1(Influenza A virus (A/turkey/Italy/8000/2002(H7N3)))
Chulalongkorn University

LigandPNGBDBM5025(Oseltamivir | US10919856, POSITIVE CONTROL | ethyl...)
Affinity DataIC50:  0.120nMpH: 6.5Assay Description:Practically in a microtitre plate, 90 μl of 33 mM MES pH 6.5 containing 4 mM CaCl2 were dispensed in each well, except for the first well of eac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed