BDBM50250146 CHEMBL522299::Ethyl 5-(4-Chlorophenyl)-2-methyl-1-(4-sulfamoylphenyl)-1H-pyrrole-3-carboxylate

SMILES CCOC(=O)c1cc(-c2ccc(Cl)cc2)n(c1C)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=NVJJSDYPFZXQGJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250146   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50250146(CHEMBL522299 | Ethyl 5-(4-Chlorophenyl)-2-methyl-1...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50250146(CHEMBL522299 | Ethyl 5-(4-Chlorophenyl)-2-methyl-1...)
Affinity DataEC50:  2.60E+3nMAssay Description:Allosteric modulator activity at alpha7 nAChR in human IMR32 cells assessed as stimulation of agonist-induced intracellular calcium level by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed