BDBM50250285 CHEMBL4091409

SMILES Clc1ccc(C(=O)NC2CCN(Cc3ccccc3C#N)CC2)c(Cl)c1

InChI Key InChIKey=PNVHAOFCDKXBDN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50250285   

TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250285(CHEMBL4091409)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250285(CHEMBL4091409)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250285(CHEMBL4091409)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250285(CHEMBL4091409)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed