BDBM50250293 CHEMBL4104682

SMILES Fc1cccc(CN2CCC(CC2)NC(=O)c2ccc(Cl)cc2Cl)c1

InChI Key InChIKey=XLDARIDHSKXNLT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50250293   

TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250293(CHEMBL4104682)
Affinity DataIC50:  3.39E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250293(CHEMBL4104682)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250293(CHEMBL4104682)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250293(CHEMBL4104682)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mus musculus)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250293(CHEMBL4104682)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed