BDBM50250951 CHEMBL4063215

SMILES Nc1nc(N)c(cc1-c1ccc(O)cc1)-c1ccc(O)cc1

InChI Key InChIKey=HWHBWHVPDARATH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50250951   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250951(CHEMBL4063215)
Affinity DataEC50:  3.65E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250951(CHEMBL4063215)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of human USP7 using UbA10 as substrate incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250951(CHEMBL4063215)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed