BDBM50250963 CHEMBL4076247

SMILES CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=ZHYXJQQBKROZDX-UHFFFAOYSA-N

Data  4 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50250963   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50250963(CHEMBL4076247)
Affinity DataIC50:  980nMAssay Description:Inhibition of full-length native C-terminal USP7 (unknown origin) using Ub-Rho110 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50250963(CHEMBL4076247)
Affinity DataIC50:  750nMAssay Description:Inhibition of native full length C-terminal USP7 (unknown origin) using ubiquitin-Rho110 as substrate pre-incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50250963(CHEMBL4076247)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human USP7 using ubiquitin-Rho as substrate incubated for 1 hrsMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50250963(CHEMBL4076247)
Affinity DataIC50:  750nMAssay Description:Inhibition of human USP7 using UbA10 as substrate incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Progenra

Curated by ChEMBL
LigandPNGBDBM50250963(CHEMBL4076247)
Affinity DataEC50:  300nMAssay Description:Inhibition of native full length C-terminal USP7 (unknown origin) using ubiquitin-Rho110 as substrate pre-incubated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair