BDBM50251070 CHEMBL464497::N-(1-benzyl-1H-benzo[d]imidazol-5-yl)-2,4,6-trimethylbenzenesulfonamide

SMILES Cc1cc(c(c(c1)C)S(=O)(=O)Nc2ccc3c(c2)ncn3Cc4ccccc4)C

InChI Key InChIKey=NZGPNMYYBHSCBR-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251070   

TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251070BDBM50251070(N-(1-benzyl-1H-benzo[d]imidazol-5-yl)-2,4,6-trimet...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human pregnane X receptor expressed in HGPXR reporter cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor subfamily 1 group I member 2(Human)
University of Montpellier

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251070BDBM50251070(N-(1-benzyl-1H-benzo[d]imidazol-5-yl)-2,4,6-trimet...)
Affinity DataEC50:  8.05nMAssay Description:Protection of human pregnane X receptor against proteolytic digestion in presence of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)