BDBM50251106 CHEMBL4064068

SMILES Clc1ccc2nc(nc(Nc3cc([nH]n3)C3CC3)c2c1)C(=O)N1CCNCC1

InChI Key InChIKey=JCJFEWWMFMUUJZ-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251106   

TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251106(CHEMBL4064068)
Affinity DataKi:  16nMAssay Description:Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251106(CHEMBL4064068)
Affinity DataKi:  2.75E+3nMAssay Description:Inhibition of human PAK1 kinase domain using coumarin and fluorescein-labeled ser/thr19 peptide as substrate preincubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251106(CHEMBL4064068)
Affinity DataKd:  16nMAssay Description:Binding affinity to biotin-labeled human truncated PAK4 kinase domain by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed