BDBM50251300 CHEMBL4066684

SMILES Cc1cc(=O)n(nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)-c1ccc(F)cc1

InChI Key InChIKey=OBFGRWOUNPRHNH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50251300   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50251300(CHEMBL4066684)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of Flt-3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50251300(CHEMBL4066684)
Affinity DataIC50:  319nMAssay Description:Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50251300(CHEMBL4066684)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50251300(CHEMBL4066684)
Affinity DataIC50:  725nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50251300(CHEMBL4066684)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50251300(CHEMBL4066684)
Affinity DataIC50:  672nMAssay Description:Inhibition of VEGFR-2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed