BDBM50251778 CHEMBL471954::endo-4-((3-(4-(2-fluorophenoxy)phenylamino)-8-aza-bicyclo[3.2.1]octan-8-yl)methyl)benzoic acid

SMILES OC(=O)c1ccc(CN2[C@H]3CC[C@@H]2C[C@@H](C3)Nc2ccc(Oc3ccccc3F)cc2)cc1

InChI Key InChIKey=UMIHWGFZSGUCOQ-NUNAXRQHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251778   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251778(CHEMBL471954 | endo-4-((3-(4-(2-fluorophenoxy)phen...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LTA4 hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251778(CHEMBL471954 | endo-4-((3-(4-(2-fluorophenoxy)phen...)
Affinity DataIC50:  40nMAssay Description:Inhibition of LTA4 hydrolase in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed