BDBM50251974 CHEMBL482086::Cyclohexyl-{4-[4-(4-fluoro-phenyl)-2-methylsulfanyl-1H-imidazol-5-yl]-pyridin-2-yl}-amine
SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCCCC2)c1
InChI Key InChIKey=GXEBQLXMNHUVPU-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50251974
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Eberhard-Karls-University Tu£Bingen
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair