BDBM50251974 CHEMBL482086::Cyclohexyl-{4-[4-(4-fluoro-phenyl)-2-methylsulfanyl-1H-imidazol-5-yl]-pyridin-2-yl}-amine

SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC2CCCCC2)c1

InChI Key InChIKey=GXEBQLXMNHUVPU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251974   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50251974(CHEMBL482086 | Cyclohexyl-{4-[4-(4-fluoro-phenyl)-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50251974(CHEMBL482086 | Cyclohexyl-{4-[4-(4-fluoro-phenyl)-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50251974(CHEMBL482086 | Cyclohexyl-{4-[4-(4-fluoro-phenyl)-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed