BDBM50252046 (2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic acid::(2S,4S)-4-(Benzyloxymethyl)glutamic Acid::CHEMBL446256

SMILES N[C@@H](C[C@@H](COCc1ccccc1)C(O)=O)C(O)=O

InChI Key InChIKey=DYMLROZAJAINNE-QWRGUYRKSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50252046   

TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252046((2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic ac...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252046((2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic ac...)
Affinity DataKi:  2.90E+5nMAssay Description:Inhibition of [3H]D-Asp uptake at human EAAT2 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252046((2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic ac...)
Affinity DataKi:  4.50E+5nMAssay Description:Inhibition of [3H]D-Asp uptake at EAAT1 in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252046((2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic ac...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of glutamate-induced depolarization in human human EAAT2 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252046((2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic ac...)
Affinity DataIC50:  3.00E+6nMAssay Description:Inhibition of glutamate-induced depolarization in human human EAAT3 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50252046((2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic ac...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of glutamate-induced depolarization in human EAAT1 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed