BDBM50252991 CHEMBL4064130

SMILES Clc1cccc(c1)-c1ccc(\C=N\NC(=O)CSc2nnc(Nc3ccccc3)s2)o1

InChI Key InChIKey=FUAOULOCZVYLFY-FSJBWODESA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50252991   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252991(CHEMBL4064130)
Affinity DataKi:  0.610nMAssay Description:Competitive inhibition of carbonic anhydrase-1 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by Lineweave...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252991(CHEMBL4064130)
Affinity DataKi:  0.770nMAssay Description:Competitive inhibition of carbonic anhydrase-1 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by Lineweave...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252991(CHEMBL4064130)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of PAK4 (unknown origin) using substrate S2 after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252991(CHEMBL4064130)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed