BDBM50253152 CHEMBL493708::N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1-methylethoxy)-6-phthalazinyl)benzamide

SMILES C[C@@H](Oc1nncc2cc(ccc12)-c1cc(ccc1C)C(=O)NC1CC1)C(F)(F)F

InChI Key InChIKey=XANMCBRIKIVXBI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50253152   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 505nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 6.05E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(N-Cyclopropyl-4-methyl-3-(1-((R)-2,2,2-trifluoro-1...)
Affinity DataIC50: 9.49E+3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed