BDBM50253229 CHEMBL445695::Isosorbide-2-(benzylcarbamate)-5-mononitrate

SMILES [O-][N+](=O)O[C@@H]1CO[C@@H]2[C@H](CO[C@H]12)OC(=O)NCc1ccccc1

InChI Key InChIKey=XCUJUZNXFHRMEC-UMSGYPCISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253229   

TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253229(CHEMBL445695 | Isosorbide-2-(benzylcarbamate)-5-mo...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human plasma BuchE after 60 mins by carbamylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50253229(CHEMBL445695 | Isosorbide-2-(benzylcarbamate)-5-mo...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human plasma BuchE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed