BDBM50254270 CHEMBL4080943

SMILES CN1CCN(CC1)c1ccc(Nc2cc(cn(C)c2=O)-c2cccc(N3CCc4c5CC(C)(C)Cc5sc4C3=O)c2CO)nc1

InChI Key InChIKey=OEPMETRTTHUBSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254270   

TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech

Curated by ChEMBL
LigandPNGBDBM50254270(CHEMBL4080943)
Affinity DataIC50:  25nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50254270(CHEMBL4080943)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human full length His-tagged BTK expressed in baculovirus expression system by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed