BDBM50254277 CHEMBL4067714

SMILES Cn1cc(cc(Nc2ccncn2)c1=O)-c1cccc(N2Cc3cc(sc3C2=O)C(C)(C)C)c1CO

InChI Key InChIKey=GNUMYJKNJPLZBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254277   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50254277(CHEMBL4067714)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human full length His-tagged BTK expressed in baculovirus expression system by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech

Curated by ChEMBL
LigandPNGBDBM50254277(CHEMBL4067714)
Affinity DataIC50:  193nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed