BDBM50254279 CHEMBL4060453
SMILES Cn1cc(cc(Nc2ccc(cn2)N2CCN(CC2)C2COC2)c1=O)-c1cccc(N2CCn3c4CCCCc4cc3C2=O)c1CO
InChI Key InChIKey=FGAHWCREJZNLBB-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50254279
Affinity DataIC50: 137nMAssay Description:Inhibition of BTK in goat F(ab')2anti-mouse IgM-stimulated Balb/c mouse splenocyte B cells assessed as suppression of BCR-mediated CD86 induction pre...More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of BTK in human B-cells assessed as decrease in BCR-stimulated B-cell proliferation after 8 hrs by [3H]-thymidine incorporation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human full length His-tagged BTK expressed in baculovirus expression system by Z-LYTE assayMore data for this Ligand-Target Pair