BDBM50254450 (S)-2-Amino-5-propionimidoylamino-pentanoic acid::CHEMBL507472::L-IPO, 13::N5-(1-iminopropyl)-L-ornithine

SMILES CCC(N)=NCCC[C@H](N)C(O)=O

InChI Key InChIKey=ZYIBCZWVLDODOL-LURJTMIESA-N

Data  4 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254450   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50254450((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
The University of Texas

LigandPNGBDBM50254450((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM50254450((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition assay using DDAH-1 and nNOS.More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM50254450((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)
Affinity DataKi:  1.45E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
The University of Texas

LigandPNGBDBM50254450((S)-2-Amino-5-propionimidoylamino-pentanoic acid |...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of human DDAH1 by plate-reader assayMore data for this Ligand-Target Pair