BDBM50254521 CHEMBL516633::N-cyclohexyl-5-methyl-N-phenyl-1-(2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)phenyl)-1H-pyrazole-3-carboxamide

SMILES Cc1cc(nn1-c1ccccc1C(=O)N1CCc2ccccc2C1)C(=O)N(C1CCCCC1)c1ccccc1

InChI Key InChIKey=AYRPCROHAVCMHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254521   

TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254521(CHEMBL516633 | N-cyclohexyl-5-methyl-N-phenyl-1-(2...)
Affinity DataIC50:  4.11E+3nMAssay Description:Inhibition of GST fused Bcl-xL (unknown origin) binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254521(CHEMBL516633 | N-cyclohexyl-5-methyl-N-phenyl-1-(2...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed