BDBM50254529 CHEMBL453466::methyl 2-((S)-2-(2-(3-(diphenylcarbamoyl)-5-methyl-1H-pyrazol-1-yl)benzoyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)acetate

SMILES COC(=O)C[C@@H]1Cc2ccccc2CN1C(=O)c1ccccc1-n1nc(cc1C)C(=O)N(c1ccccc1)c1ccccc1

InChI Key InChIKey=CUIQYYXLEMZWRC-PMERELPUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254529   

TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254529(CHEMBL453466 | methyl 2-((S)-2-(2-(3-(diphenylcarb...)
Affinity DataIC50:  5.17E+3nMAssay Description:Inhibition of GST fused Bcl-xL (unknown origin) binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50254529(CHEMBL453466 | methyl 2-((S)-2-(2-(3-(diphenylcarb...)
Affinity DataIC50:  280nMAssay Description:Inhibition of GST fused Bcl-2 (unknown origin) binding to biotinylated 16 mer Bak-BH3 peptide by HTRF-LANCE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed