BDBM50254568 (2S,6S,11S)-6,11-Dimethyl-3-[(S)-1-(tetrahydro-furan-2-yl)methyl]-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL517166

SMILES C[C@@H]1[C@@H]2Cc3ccc(cc3[C@@]1(C)CCN2C[C@@H]1CCCO1)C(N)=O

InChI Key InChIKey=OWRBBFHZDDJXIW-BPODSCFKSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254568   

TargetMu-type opioid receptor(GUINEA PIG)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50254568((2S,6S,11S)-6,11-Dimethyl-3-[(S)-1-(tetrahydro-fur...)
Affinity DataKi:  0.0520nMAssay Description:Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50254568((2S,6S,11S)-6,11-Dimethyl-3-[(S)-1-(tetrahydro-fur...)
Affinity DataKi:  0.0890nMAssay Description:Displacement of [3H]U69593 form kappa opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50254568((2S,6S,11S)-6,11-Dimethyl-3-[(S)-1-(tetrahydro-fur...)
Affinity DataIC50:  58nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50254568((2S,6S,11S)-6,11-Dimethyl-3-[(S)-1-(tetrahydro-fur...)
Affinity DataEC50:  30nMAssay Description:Activity at human cloned kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed