BDBM50254784 CHEMBL517179::N5-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl)-N7-((R)-1-phenylethyl)chroman-5,7-dicarboxamide

SMILES C[C@@H](NC(=O)c1cc2OCCCc2c(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1CC1)c1ccccc1

InChI Key InChIKey=HQIFKDQCICONGY-SPTGULJVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254784   

TargetBeta-secretase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254784(CHEMBL517179 | N5-((2S,3R)-4-(cyclopropylamino)-3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254784(CHEMBL517179 | N5-((2S,3R)-4-(cyclopropylamino)-3-...)
Affinity DataIC50:  112nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed