BDBM50255040 1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methyl)-3,5-dimethyl-2-oxo-1,3-oxazinan-5-yl)-3-(3-(1-methyl-1H-tetrazol-5-yl)phenyl)urea::CHEMBL505914::CHEMBL518571

SMILES CN1CC(C)(NC(=O)Nc2cccc(c2)-c2nnnn2C)C(CN2CCC[C@@H](Cc3ccc(F)cc3)C2)OC1=O

InChI Key InChIKey=OTSUKARJPJAFRM-UEHGGBRMSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50255040   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of human ERG by calcium-flux based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  0.150nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50255040(1-(6-(((S)-3-(4-fluorobenzyl) piperidin-1-yl)methy...)
Affinity DataIC50:  0.120nMAssay Description:Binding affinity to CCR3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed