BDBM50256169 (S)-2-cyclohexyl-2-(3-(3-mesitylureido)-2-naphthamido)propanoic acid::2-cyclohexyl-N-[(3-{[(2,4,6-trimethylphenyl)carbamoyl]amino}naphthalen-2-yl)carbonyl]-D-alanine::CHEMBL482146

SMILES Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)N[C@@](C)(C2CCCCC2)C(O)=O)c(C)c1

InChI Key InChIKey=ZYHGLTOSKWXGQM-PMERELPUSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50256169   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256169((S)-2-cyclohexyl-2-(3-(3-mesitylureido)-2-naphtham...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human liver glycogen phosphorylase A by fluorescence intensity endpoint assay in presence of glucoseMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256169((S)-2-cyclohexyl-2-(3-(3-mesitylureido)-2-naphtham...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256169((S)-2-cyclohexyl-2-(3-(3-mesitylureido)-2-naphtham...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human liver glycogen phosphorylase A in HepG2 cells assessed as forskolin-induced glycogenolysisMore data for this Ligand-Target Pair