BDBM50257636 5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine::CHEMBL526307

SMILES COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1I

InChI Key InChIKey=AATPYXMXFBBKFO-UHFFFAOYSA-N

Data  4 KI  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257636   

TargetP2X purinoceptor 3(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50257636(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human recombinant P2X3 receptor expressed in HEK293-Tet-on cells assessed as alpha,beta-methylene-ATP-stimulated Ca2+ influx b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50257636(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human recombinant P2X3 receptor expressed in HEK293-Tet-on cells assessed as alpha,beta-methylene-ATP-stimulated Ca2+ influx b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed