BDBM50257818 CHEMBL4096327

SMILES Nc1nc(N[C@@H]2CC[C@@H](O)[C@H]2O)c2c(c[nH]c2n1)C#N

InChI Key InChIKey=XINWVEOLLNEWDD-BHNWBGBOSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257818   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257818(CHEMBL4096327)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257818(CHEMBL4096327)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed