BDBM50257820 CHEMBL4104970

SMILES Nc1nc(-c2ccc(O)cc2)c2c(c[nH]c2n1)C#N

InChI Key InChIKey=MIUAEOAFMQTRDO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257820   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257820(CHEMBL4104970)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257820(CHEMBL4104970)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed