BDBM50257884 CHEMBL4065551

SMILES CS(=O)(=O)Nc1ccc(cc1)-c1nc(N)nc2[nH]cc(C#N)c12

InChI Key InChIKey=PASZHMUXXHIBCC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257884   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257884(CHEMBL4065551)
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant full length human IKKbeta expressed in baculovirus infected sf9 insect cells using biotinylated IkBalpha as substrate after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50257884(CHEMBL4065551)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged IKKalpha (1 to 745 residues) expressed in baculovirus expression system using biotinylated IkBa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed