BDBM50257919 CHEMBL493960::N-(2-(7-(3,4-dichlorobenzylamino)-3-(4-methoxyphenyl)-2-oxoquinoxalin-1(2H)-yl)ethyl)acetamide

SMILES COc1ccc(cc1)-c1nc2ccc(NCc3ccc(Cl)c(Cl)c3)cc2n(CCNC(C)=O)c1=O

InChI Key InChIKey=FPQQMWRUQKWZCF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257919   

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257919(CHEMBL493960 | N-(2-(7-(3,4-dichlorobenzylamino)-3...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of Delta9-desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA (8-3)-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257919(CHEMBL493960 | N-(2-(7-(3,4-dichlorobenzylamino)-3...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta5-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257919(CHEMBL493960 | N-(2-(7-(3,4-dichlorobenzylamino)-3...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50257919(CHEMBL493960 | N-(2-(7-(3,4-dichlorobenzylamino)-3...)
Affinity DataIC50:  110nMAssay Description:Inhibition of stearoyl-CoA delta9 desaturase in rat microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Rattus norvegicus)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50257919(CHEMBL493960 | N-(2-(7-(3,4-dichlorobenzylamino)-3...)
Affinity DataIC50: >30nMAssay Description:Inhibition of rat microsomal Delta6-desaturaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed