BDBM50258076 CHEMBL494843::N-(4-(N-benzyl-2-chlorophenylsulfonamido)-2-chlorophenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
SMILES CC(O)(C(=O)Nc1ccc(cc1Cl)N(Cc1ccccc1)S(=O)(=O)c1ccccc1Cl)C(F)(F)F
InChI Key InChIKey=XUPXFYHPDJNHNA-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50258076
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human LXRbeta expressed in human SH-SY5Y cells co-transfected with Gal4-LBD after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human LXRalpha expressed in human SH-SY5Y cells cotransfected with Gal4-LBD after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Astrazeneca R&D SöDertäLje
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at LXRalpha ligand binding domain by FRET based SRC1 recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: 880nMAssay Description:Agonist activity at LXRbeta ligand binding domain (unknown origin) by FRET based SRC1 recruitment assayMore data for this Ligand-Target Pair