BDBM50258514 CHEMBL4062015

SMILES CC(=O)\C=C\[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=BJEZNOLUMLFYHR-DEOGAWDZSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50258514   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50258514(CHEMBL4062015)
Affinity DataKi:  0.0740nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesiense rhodesain expressed in Pichia pastoris using Cbz-Phe-Arg-AMC as substrate after 30 min by fl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University of Messina

Curated by ChEMBL
LigandPNGBDBM50258514(CHEMBL4062015)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain 2(Plasmodium falciparum)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50258514(CHEMBL4062015)
Affinity DataIC50:  780nMAssay Description:Inhibition of recombinant Plasmodium falciparum falcipain-2 expressed in Escherichia coli M15(pREP4) using Cbz-Phe-Arg-AMC as substrate by fluorescen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed