BDBM50258647 CHEMBL512644::N1-(biphenyl-4-yl)-N8-hydroxyoctanediamide

SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=MIYLHRAVWYBTPV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258647   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258647(CHEMBL512644 | N1-(biphenyl-4-yl)-N8-hydroxyoctane...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258647(CHEMBL512644 | N1-(biphenyl-4-yl)-N8-hydroxyoctane...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258647(CHEMBL512644 | N1-(biphenyl-4-yl)-N8-hydroxyoctane...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50258647(CHEMBL512644 | N1-(biphenyl-4-yl)-N8-hydroxyoctane...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed