BDBM50259228 (1S,2R)-1-(methyl(o-tolyl)amino)-3-(methylamino)-1-phenylpropan-2-ol::(R,S/S,R)-syn-1-(methyl(o-tolyl)amino)-3-(methylamino)-1-phenylpropan-2-ol::CHEMBL469150

SMILES CNC[C@@H](O)[C@@H](N(C)c1ccccc1C)c1ccccc1

InChI Key InChIKey=VIHUCKRDYCSWQL-MSOLQXFVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50259228   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259228((1S,2R)-1-(methyl(o-tolyl)amino)-3-(methylamino)-1...)
Affinity DataIC50:  217nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259228((1S,2R)-1-(methyl(o-tolyl)amino)-3-(methylamino)-1...)
Affinity DataIC50:  2.61E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259228((1S,2R)-1-(methyl(o-tolyl)amino)-3-(methylamino)-1...)
Affinity DataIC50:  217nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50259228((1S,2R)-1-(methyl(o-tolyl)amino)-3-(methylamino)-1...)
Affinity DataIC50:  2.61E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed