BDBM50259413 CHEMBL4105084
SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(Cl)c3)n2n1
InChI Key InChIKey=KAGWQDFFFLWBFD-ZDUSSCGKSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50259413
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University of Paris
Curated by ChEMBL
University of Paris
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of GST tagged recombinant human DYRK2 expressed in Escherichia coli using using woodtide as substrate after 30 mins by [gamma-33P]ATP base...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against dipeptidyl peptidase IVMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Paris
Curated by ChEMBL
University of Paris
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of GST tagged recombinant human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of GST tagged recombinant mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Paris
Curated by ChEMBL
University of Paris
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of GST tagged recombinant human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST tagged recombinant mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of GST tagged recombinant mouse CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of Paris
Curated by ChEMBL
University of Paris
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
University of Paris
Curated by ChEMBL
University of Paris
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of GST tagged recombinant human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based scin...More data for this Ligand-Target Pair