BDBM50259415 CHEMBL4061526

SMILES CC[C@@H](CO)Nc1ccc2ncc(-c3cccc(NC(C)=O)c3)n2n1

InChI Key InChIKey=YGXHQYJKJUFSJI-AWEZNQCLSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50259415   

TargetDual specificity protein kinase CLK3(Mus musculus)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  280nMAssay Description:Inhibition of GST tagged recombinant mouse CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  27nMAssay Description:Inhibition of human CLK4More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  39nMAssay Description:Inhibition of GST tagged recombinant human DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Mus musculus)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  27nMAssay Description:Inhibition of GST tagged recombinant mouse CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  28nMAssay Description:Inhibition of GST tagged recombinant mouse CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  38nMAssay Description:Inhibition of GST tagged recombinant human DYRK1B expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  43nMAssay Description:Inhibition of GST tagged recombinant human DYRK2 expressed in Escherichia coli using using woodtide as substrate after 30 mins by [gamma-33P]ATP base...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  110nMAssay Description:Inhibition of GST tagged recombinant human DYRK3 expressed in Escherichia coli using woodtide as substrate after 30 mins by [gamma-33P]ATP based scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant CDK5/p25 after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant CDK2/cyclin A after 30 mins by [gamma-33P]ATP based scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))TBA
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  280nMAssay Description:Inhibition of human CLK3More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  28nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))TBA
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  28nMAssay Description:Inhibition of human CLK2More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK2(Mus musculus)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50259415(CHEMBL4061526)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against dipeptidyl peptidase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed