BDBM50260307 CHEMBL4089550

SMILES COc1cc2CCN(CC3CCN(Cc4cc(C)cc(\C=N\O)c4O)CC3)Cc2cc1OC

InChI Key InChIKey=SVJSIJFMMFYJHR-MZJWZYIUSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260307   

TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260307(CHEMBL4089550)
Affinity DataKd:  7.60E+3nMAssay Description:Reactivation of tabun-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260307(CHEMBL4089550)
Affinity DataIC50:  4.18E+5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured every 5 mins for 20 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260307(CHEMBL4089550)
Affinity DataKd:  3.80E+4nMAssay Description:Reactivation of tabun-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Fourth Military Medical University

Curated by ChEMBL
LigandPNGBDBM50260307(CHEMBL4089550)
Affinity DataKd:  2.30E+4nMAssay Description:Reactivation of tabun-induced inhibition of human AChE assessed as dissociation constant using acetylthiocholine as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed