BDBM50261215 CHEMBL2387223
SMILES F[C@@H]1C[C@@H]1C(=O)Nc1cc(NC(=O)c2c(F)cc(cc2Cl)C#N)ccn1
InChI Key InChIKey=NKALKXMQBFLGQI-CMPLNLGQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50261215
Affinity DataKi: 1.60nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-23 induced STAT3 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Inhibition of JAK2 (unknown origin) assessed as reduction in EPO-mediated STAT5 phosphorylation by cell based readout assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.25E+3nMAssay Description:Inhibition of JAK2 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
Affinity DataEC50: 224nMAssay Description:Inhibition of TYK2 (unknown origin) assessed as reduction in IL-12 induced STAT4 phosphorylation by cell based ELISAMore data for this Ligand-Target Pair