BDBM50261807 CHEMBL4086461

SMILES NC(=O)c1cc(Cl)c2c(Cl)c(C3CC3)n([C@@H]3CCCNC3)c2n1

InChI Key InChIKey=DAGZBPRGFBEYDJ-SECBINFHSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50261807   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261807(CHEMBL4086461)
Affinity DataIC50:  4nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261807(CHEMBL4086461)
Affinity DataIC50:  22nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261807(CHEMBL4086461)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261807(CHEMBL4086461)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261807(CHEMBL4086461)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed