BDBM50261808 CHEMBL4104355
SMILES NC(=O)c1cc(Cl)c2c(Cl)c(C3CC3)n([C@H]3CCCNC3)c2n1
InChI Key InChIKey=DAGZBPRGFBEYDJ-VIFPVBQESA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50261808
Affinity DataIC50: 43nMAssay Description:Inhibition of PIM1 in human KG1 cells assessed as reduction in BAD phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sanofi Genzyme
Curated by ChEMBL
Sanofi Genzyme
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of full length human His-tagged BTK expressed in baculovirus expression system using GEEPLYWSFPAKKK-NH2 as substrate measured immediately ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using testosterone as substrateMore data for this Ligand-Target Pair