BDBM50261815 2-(3,4-dimethoxyphenyl)-3-fluoroprop-2-en-1-amine::CHEMBL445285

SMILES COc1ccc(cc1OC)C(\CN)=C/F

InChI Key InChIKey=HLNSVKSSCLHOSW-TWGQIWQCSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261815   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50261815(2-(3,4-dimethoxyphenyl)-3-fluoroprop-2-en-1-amine ...)
Affinity DataKi:  2.31E+5nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))TBA
LigandPNGBDBM50261815(2-(3,4-dimethoxyphenyl)-3-fluoroprop-2-en-1-amine ...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] A/B(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50261815(2-(3,4-dimethoxyphenyl)-3-fluoroprop-2-en-1-amine ...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory activity against rat brain mitochondrial Monoamine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Rattus norvegicus (Rat))
UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50261815(2-(3,4-dimethoxyphenyl)-3-fluoroprop-2-en-1-amine ...)
Affinity DataIC50:  6nMAssay Description:Inhibition of rat CAOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed