BDBM50261855 CHEMBL4092706

SMILES NC(=O)c1cc(Cl)c2c(Cl)c(-c3ccccc3)n(C3CCCNC3)c2n1

InChI Key InChIKey=LMUQPBXEPPNVJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261855   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261855(CHEMBL4092706)
Affinity DataIC50:  13nMAssay Description:Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Sanofi Genzyme

Curated by ChEMBL
LigandPNGBDBM50261855(CHEMBL4092706)
Affinity DataIC50:  109nMAssay Description:Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed